…And my other Ph.D. adviser, Martin J. Kushmerick

July 14, 2019


image taken from http://depts.washington.edu/tcmi/

In my haste to note the passing of Kevin Conley, my primary graduate school adviser, I failed to mention a sad coincidence, which is that my OTHER graduate school adviser had just died eight days earlier.

Marty Kushmerick was, in a word, brilliant.  He knew a lot about a lot of things; breadth and depth coexisted happily in his brain.  Though his field was muscle biology, he taught himself way more thermodynamics, mathematical modeling, and nuclear physics than the average muscle biologist (e.g., me) could ever dream of. This allowed him to ask all sorts of scientific questions and collaborate with all sorts of people, who found his brilliance both charming and useful.

Kevin was one such person.

Two of Kevin’s greatest studies (Conley et al. 1997 and 1998) dismantled the prevailing model of the control of glycolysis in skeletal muscle. These studies were based on the fact that glycolysis produces lactic acid, which lowers the pH, which can be measured with 31P NMR spectroscopy, our lab’s primary technique at the time. However, it’s awfully hard to calculate precise RATES of glycolysis, as Kevin needed to do. I don’t think Kevin could have navigated the arcane details of proton stoichiometry on his own; fortunately, he had Marty to do the math (Kushmerick 1997) and thus provide the foundation for his own work.

While Kevin and Marty had distinct strengths and personalities, they shared a sincere and profound enthusiasm for the day-to-day work of scientific research. This was obvious to all who knew them.  They were visibly excited when they found an insightful paper in the literature or thought of a new experiment to try. It was fun to be in their lab in the late ’90s and early ’00s in part because THEY were having fun.

Fifteen-plus years later, it’s hard for me to conjure up that atmosphere, to remember what it felt like. This song helps, though. (Marty makes a cameo at 2:33.)


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